As a chemical, helium is pretty boring. As a noble gas, it's pretty tough to get it to react with anything. However, it's lighter than air, and safer than hydrogen, so it's regularily used to fill balloons. And get this, it's actually mined from the ground.
The best use of helium, once it has passed its useful life as a balloon-weight-reducer, is to breathe it in. As you well know, this makes your voice sound pretty funny. It has to do with the different speed of sound in helium, which changes the way the waves are created in your larynx...
Well, that's about all I have to say about this lovely second element. I'll be back tomorrow with stories about lithium.